Serophene

Generic Name: clomiphene (KLOE mih feen)

Brand Names: Clomid, Serophene

What is Serophene (clomiphene)?

Clomiphene stimulates the release of hormones necessary for ovulation to occur.

Clomiphene is used to stimulate ovulation (the release of an egg) when a woman's ovaries can produce a follicle but hormonal stimulation is deficient.

Clomiphene may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Serophene (clomiphene)?

Use caution when driving, operating machinery, or performing other hazardous activities. Clomiphene may cause blurred vision or other visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.

Clomiphene may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

Who should not take Serophene (clomiphene)?

Do not take clomiphene without first talking to your doctor if you

• 
  

  might be pregnant;

  
  


• 
  

  have a thyroid problem or another endocrine disorder;

  
  


• 
  

  have undiagnosed vaginal bleeding;

  
  


• 
  

  have endometriosis or endometrial carcinoma;

  
  


• 
  

  have uterine fibroids;

  
  


• 
  

  have liver disease;

  
  


• 
  

  have ovarian cysts or ovarian enlargement not due to polycystic ovarian syndrome; or

  
  


• 
  

  have any other serious or chronic medical illness.

  
  

You may not be able to take clomiphene, or you may require a lower dose or special monitoring if you have any of the conditions listed above.

Do not take clomiphene if you are pregnant. Clomiphene is in the FDA pregnancy category X. This means that it is known to cause birth defects. It is not known whether clomiphene pass into breast milk. Do not take clomiphene without first talking to your doctor if you are breast-feeding a baby.

How should I take Serophene (clomiphene)?

Use clomiphene exactly as directed by your doctor. If you do not understand these directions, ask your doctor, nurse, or pharmacist to explain them to you.

Take each dose with a full glass of water.

Clomiphene is usually taken in 5 day cycles. Follow your doctor's instructions.

Store clomiphene at room temperature, away from direct light, moisture, and heat.

See also: Serophene dosage (in more detail)

What happens if I miss a dose?

Contact your doctor if you miss a dose of clomiphene.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a clomiphene overdose include nausea, vomiting, flushing, blurred vision, visual spots or flashes, and abdominal pain.

What should I avoid while taking Serophene (clomiphene)?

Use caution when driving, operating machinery, or performing other hazardous activities. Clomiphene may cause blurred vision or other visual side effects during or shortly after therapy. Notify your doctor immediately if you develop any visual side effects and use caution when performing hazardous activities, especially under conditions of variable lighting.

Serophene (clomiphene) side effects

Stop taking clomiphene and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

The ovarian hyperstimulation syndrome (OHSS) has been reported to occur in patients receiving clomiphene. Symptoms of OHSS include swelling of the hands or legs, abdominal pain and swelling, shortness of breath, weight gain, and nausea or vomiting. OHSS can be fatal. Notify your doctor immediately or seek emergency medical attention if you develop any of these side effects.

Other side effects may also occur. Notify your doctor if you experience

• 
  

  ovarian enlargement presenting as abdominal or pelvic pain, tenderness, pressure, or swelling;

  
  


• 
  

  flushing;

  
  


• 
  

  nausea, vomiting, or diarrhea;

  
  


• 
  

  breast tenderness or discomfort;

  
  


• 
  

  blurred vision or other visual disturbances;

  
  


• 
  

  headache; or

  
  


• 
  

  abnormal uterine bleeding.

  
  

Clomiphene may increase the likelihood of multiple births. Multiple births may carry additional risk both for the mother and for the fetuses.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Serophene (clomiphene)?

There are no known interactions between clomiphene and other medicines. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

More Serophene resources

• Serophene Side Effects (in more detail)
• Serophene Dosage
• Serophene Use in Pregnancy & Breastfeeding
• Serophene Support Group
• 0 Reviews for Serophene - Add your own review/rating

• Serophene Prescribing Information (FDA)


• Serophene Advanced Consumer (Micromedex) - Includes Dosage Information


• Serophene MedFacts Consumer Leaflet (Wolters Kluwer)


• Clomid Prescribing Information (FDA)


• Clomid Consumer Overview


• Clomiphene Prescribing Information (FDA)


• Clomiphene Citrate Monograph (AHFS DI)

Compare Serophene with other medications

• Female Infertility
• Lactation Suppression
• Oligospermia
• Ovulation Induction

Where can I get more information?

• Your pharmacist has additional information about clomiphene written for health professionals that you may read.

See also: Serophene side effects (in more detail)

Shelter Tinted

Generic Name: octinoxate, octisalate, oxybenzone and titanium dioxide

Dosage Form: cream
DRUG FACTS

WATER (AQUA)

C12-15 ALKYL BENZOATE

CYCLOPENTASILOXANE

GLYCERIN

STEARETH-21

DIMETHICONE

METHYL METHACRYLATE/GLYCOL DIMETHACRYLATE CROSSPOLYMER

BEHENYL ALCOHOL

HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER

DIMETHICONE CROSSPOLYMER

STEARETH-2

RETINYL PALMITATE

PHYTOSTEROLS

TOCOTRIENOLS

TOCOPHEROL

SQUALENE

ORYZA SATIVA (RICE) BRAN WAX

PALMITOYL OLIGOPEPTIDE

PALMITOYL TETRAPEPTIDE-7

RUBUS FRUITICOSUS (BLACKBERRY) LEAF EXTRACT

MELANIN

LAVANDULA AUGUSTIFOLIA (LAVENDER) OIL

ALOE BARBADENSIS LEAF JUICE

MALTODEXTRIN

CARBOMER

BUTYLENE GLYCOL

POLYSORBATE 20

SIMETHICONE

ALUMINA

SORBITAN LAURATE

DISODIUM EDTA

CHLORPHENESIN

PHENOXYETHANOL

TRIETHOXYCAPRYLYLSILANE

IRON OXIDES

ASK DOCTOR IF RASH OR IRRITATION DEVELOPS AND LASTS

WHEN USING THIS PRODUCT.  KEEP OUT OF EYES, RINSE WITH WATER TO REMOVE.

STOP USE AND ASK A DOCTOR IS RASH OCCURS AND LASTS.

KEEP OUT OF REACH OF CHILDREN, IF SWALLOWED GET MEDICAL HELP OR CONTACT A POISON CENTER RIGHT AWAY

Shelter Tinted  octinoxate, octisalate, oxybenzone, titanium dioxide  cream

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 50184-4700 Route of Administration TOPICAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength octinoxate (octinoxate) octinoxate 75 mg  in 1 g OCTISALATE (OCTISALATE) OCTISALATE 50 mg  in 1 g OXYBENZONE (OXYBENZONE) OXYBENZONE 50 mg  in 1 g TITANIUM DIOXIDE (TITANIUM) TITANIUM DIOXIDE 10 mg  in 1 g

Inactive Ingredients Ingredient Name Strength WATER   C12-15 ALKYL BENZOATE   CYCLOMETHICONE 5   GLYCERIN   STEARETH-21   DIMETHICONE   METHYL METHACRYLATE   DOCOSANOL   STEARETH-2   VITAMIN A PALMITATE   ALPHA-TOCOPHEROL   SQUALENE   RICE BRAN   RUBUS FRUTICOSUS LEAF   ENGLISH LAVENDER OIL   ALOE VERA LEAF   MALTODEXTRIN   CARBOMER 934   BUTYLENE GLYCOL   POLYSORBATE 20   ALUMINUM OXIDE   SORBITAN MONOLAURATE   EDETATE DISODIUM   CHLORPHENESIN   PHENOXYETHANOL   OCTYLTRIETHOXYSILANE   FERRIC OXIDE YELLOW   FERRIC OXIDE RED

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 50184-4700-2 1 TUBE In 1 BOX contains a TUBE (50184-4700-1) 1 50184-4700-1 56.7 g In 1 TUBE This package is contained within the BOX (50184-4700-2)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
OTC monograph not final	part352	09/14/2004

Labeler - Philosophy, Inc. (948102256)

Establishment
Name	Address	ID/FEI	Operations
Philosophy Inc for BioTech Research Labs		948102256	manufacture

Revised: 02/2010Philosophy, Inc.

More Shelter Tinted resources

• Shelter Tinted Side Effects (in more detail)
• Shelter Tinted Support Group
• 0 Reviews · Be the first to review/rate this drug

Silace

Generic Name: docusate (DOK ue sate)

Brand Names: Calcium Stool Softener, Colace, Correctol Softgel Extra Gentle, D-S Caps, Diocto, Doc-Q-Lace, Docu, Docu Soft, Doculase, Docusoft S, DocuSol, DOK, DOS, DSS, Dulcolax Stool Softener, Enemeez Mini, Fleet Sof-Lax, Kao-Tin, Kaopectate Stool Softener, Kasof, Phillips Stool Softener, Silace, Sur-Q-Lax

What is Silace (docusate)?

Docusate is a stool softener. It makes bowel movements softer and easier to pass.

Docusate is used to treat or prevent constipation, and to reduce pain or rectal damage caused by hard stools or by straining during bowel movements.

Docusate may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Silace (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist before using docusate if you are on a low-salt diet, if you are pregnant or breast-feeding, or if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

What should I discuss with my healthcare provider before using Silace (docusate)?

You should not use docusate if you are allergic to it, or if you have a blockage in your intestines. Do not use docusate while you are sick with nausea, vomiting, or stomach pain. Do not take mineral oil while using docusate, unless your doctor tells you to.

Ask a doctor or pharmacist if it is safe for you to take docusate:

• 
  

  if you are on a low-salt diet; or

  
  


• 
  

  if you have recently had a sudden change in your bowel habits lasting for longer than 2 weeks.

  
  

It is not known whether docusate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether docusate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old without the advice of a doctor.

How should I use Silace (docusate)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Take docusate tablets or capsules with a full glass of water. Drink plenty of liquids while you are taking docusate. Do not crush, chew, or break a docusate capsule. Swallow it whole.

Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. Mix the liquid with 6 to 8 ounces of milk, fruit juice, or infant formula and drink the mixture right away.

Do not take docusate rectal enema by mouth. It is for use only in your rectum. Wash your hands before and after using docusate rectal enema.

Try to empty your bowel and bladder just before using the enema.

Twist off the applicator tip. Lie down on your left side with your knees bent, and gently insert the tip of the enema applicator into the rectum. Squeeze the tube to empty the entire contents into the rectum. Throw away the tube, even if there is still some medicine left in it.

After using docusate, you should have a bowel movement within 12 to 72 hours. Call your doctor if you have not had a bowel movement within 1 to 3 days.

Do not use docusate for longer than 7 days unless your doctor has told you to. Overuse of a stool softener can lead to serious medical problems. Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since docusate is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting or stomach pain.

What should I avoid while using Silace (docusate)?

Avoid using laxatives or other stool softeners unless your doctor has told you to.

Avoid using the bathroom just after using docusate enema.

Silace (docusate) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using docusate and call your doctor at once if you have a serious side effect such as:

• 
  

  rectal bleeding or irritation;

  
  


• 
  

  numbness or a rash around your rectum;

  
  


• 
  

  severe diarrhea or stomach cramps; or

  
  


• 
  

  continued constipation.

  
  

Less serious side effects may include:

• 
  

  mild diarrhea; or

  
  


• 
  

  mild nausea.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Silace (docusate)?

There may be other drugs that can interact with docusate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Silace resources

• Silace Side Effects (in more detail)
• Silace Use in Pregnancy & Breastfeeding
• Silace Drug Interactions
• Silace Support Group
• 0 Reviews for Silace - Add your own review/rating

• Docusate Professional Patient Advice (Wolters Kluwer)


• Colace MedFacts Consumer Leaflet (Wolters Kluwer)


• Diocto Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Docusate Salts Monograph (AHFS DI)


• Dostinex Monograph (AHFS DI)


• Enemeez Mini Enema MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Silace with other medications

• Constipation

Where can I get more information?

• Your pharmacist can provide more information about docusate.

See also: Silace side effects (in more detail)

Siladryl Allergy

Generic Name: diphenhydramine (DYE fen HYE dra meen)

Brand Names: Aler-Tab, Allergy, Allermax, Altaryl, Benadryl Allergy, Benadryl DF, Benadryl Dye Free Allergy, Benadryl Ultratab, Children's Allergy, Diphen Cough, Diphenhist, Dytuss, PediaCare Children's Allergy, Q-Dryl, Q-Dryl A/F, Siladryl, Siladryl Allergy, Silphen Cough, Simply Sleep, Sleep-ettes, Sleep-ettes D, Sominex Maximum Strength Caplet, Theraflu Thin Strips Multi Symptom, Triaminic Thin Strips Cough & Runny Nose, Unisom Sleepgels Maximum Strength, Valu-Dryl

What is Siladryl Allergy (diphenhydramine)?

Diphenhydramine is an antihistamine. Diphenhydramine blocks the effects of the naturally occurring chemical histamine in the body.

Diphenhydramine is used to treat sneezing; runny nose; itching, watery eyes; hives; rashes; itching; and other symptoms of allergies and the common cold.

Diphenhydramine is also used to suppress coughs, to treat motion sickness, to induce sleep, and to treat mild forms of Parkinson's disease.

Diphenhydramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Siladryl Allergy (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

What should I discuss with my healthcare provider before taking Siladryl Allergy (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• 
  

  glaucoma or increased pressure in the eye;

  
  


• 
  

  a stomach ulcer;

  
  


• 
  

  an enlarged prostate, bladder problems or difficulty urinating;

  
  


• 
  

  an overactive thyroid (hyperthyroidism);

  
  


• 
  

  hypertension or any type of heart problems; or

  
  


• 
  

  asthma.

  
  

You may not be able to take diphenhydramine, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.

Diphenhydramine is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take diphenhydramine without first talking to your doctor if you are pregnant. Infants are especially sensitive to the effects of antihistamines, and side effects could occur in a breast-feeding baby. Do not take diphenhydramine without first talking to your doctor if you are nursing a baby. If you are over 60 years of age, you may be more likely to experience side effects from diphenhydramine. You may require a lower dose of this medication.

How should I take Siladryl Allergy (diphenhydramine)?

Take diphenhydramine exactly as directed on the package or as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Diphenhydramine can be taken with or without food.

For motion sickness, a dose is usually taken 30 minutes before motion, then with meals and at bedtime for the duration of exposure.

As a sleep aid, diphenhydramine should be taken approximately 30 minutes before bedtime.

To ensure that you get a correct dose, measure the liquid forms of diphenhydramine with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Never take more of this medication than is prescribed for you. The maximum amount of diphenhydramine that you should take in any 24-hour period is 300 mg.

Store diphenhydramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

What happens if I overdose?

Seek emergency medical attention if an overdose is suspected.

Symptoms of a diphenhydramine overdose include extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever, shaking, insomnia, hallucinations, and possibly seizures.

What should I avoid while taking Siladryl Allergy (diphenhydramine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking diphenhydramine.

Siladryl Allergy (diphenhydramine) side effects

Stop taking diphenhydramine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take diphenhydramine and talk to your doctor if you experience

• 
  

  sleepiness, fatigue, or dizziness;

  
  


• 
  

  headache;

  
  


• 
  

  dry mouth; or

  
  


• 
  

  difficulty urinating or an enlarged prostate.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Siladryl Allergy (diphenhydramine)?

Do not take diphenhydramine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A very dangerous drug interaction could occur, leading to serious side effects.

Talk to your pharmacist before taking other over-the-counter cough, cold, allergy, or insomnia medications. These products may contain medicines similar to diphenhydramine, which could lead to an antihistamine overdose.

Before taking this medication, tell your doctor if you are taking any of the following medicines:

• 
  

  anxiety or sleep medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

  
  


• 
  

  medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil); or

  
  


• 
  

  any other medications that make you feel drowsy, sleepy, or relaxed.

  
  

Drugs other than those listed here may also interact with diphenhydramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

More Siladryl Allergy resources

• Siladryl Allergy Side Effects (in more detail)
• Siladryl Allergy Use in Pregnancy & Breastfeeding
• Siladryl Allergy Drug Interactions
• 0 Reviews for Siladryl Allergy - Add your own review/rating

• Banophen MedFacts Consumer Leaflet (Wolters Kluwer)


• Ben-Tann Suspension MedFacts Consumer Leaflet (Wolters Kluwer)


• Benadryl Consumer Overview


• Benadryl Cream MedFacts Consumer Leaflet (Wolters Kluwer)


• Benadryl Allergy Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Children's Allergy Prescribing Information (FDA)


• Diphen Advanced Consumer (Micromedex) - Includes Dosage Information


• Diphenhydramine MedFacts Consumer Leaflet (Wolters Kluwer)


• Diphenhydramine Prescribing Information (FDA)


• Diphenhydramine Hydrochloride Monograph (AHFS DI)


• Diphenoxylate Hydrochloride Monograph (AHFS DI)


• Dytuss Elixir MedFacts Consumer Leaflet (Wolters Kluwer)


• Simply Sleep MedFacts Consumer Leaflet (Wolters Kluwer)


• Sominex MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Siladryl Allergy with other medications

• Allergic Reactions
• Cold Symptoms
• Cough
• Extrapyramidal Reaction
• Hay Fever
• Insomnia
• Motion Sickness
• Nausea/Vomiting
• Pruritus
• Urticaria

Where can I get more information?

• Your pharmacist can provide more information about diphenhydramine.

See also: Siladryl Allergy side effects (in more detail)

sevelamer

Generic Name: sevelamer (se VEL a mer)

Brand Names: Renagel, Renvela

What is sevelamer?

Sevelamer is a phosphate binder. Sevelamer helps prevent hypocalcemia (low levels of calcium in the body) caused by elevated phosphorus.

Sevelamer is used to reduce blood levels of phosphorus in people with chronic kidney disease who are on dialysis.

Sevelamer may also be used for purposes not listed in this medication guide.

What is the most important information I should know about sevelamer?

You should not take this medication if you are allergic to sevelamer, or if you have a bowel obstruction.

Before taking sevelamer, tell your doctor if you have trouble swallowing, severe constipation, a blockage in your intestines, a stomach or intestinal disorder, or if you have recently had stomach or intestinal surgery.

Avoid taking any other medicines within 1 hour before or 3 hours after you take sevelamer. Sevelamer can bind to other medications and make them less effective.

Before taking sevelamer, tell your doctor if you are taking ciprofloxacin (Cipro), a heart rhythm medication, or a seizure medication.

Do not take calcium or other mineral supplements without your doctor's advice. Use only the specific type of calcium or mineral supplement your doctor recommends.

What should I discuss with my healthcare provider before taking sevelamer?

You should not take this medication if you are allergic to sevelamer, or if you have a bowel obstruction.

To make sure you can safely take sevelamer, tell your doctor if you have any of these other conditions:

• 
  

  trouble swallowing;

  
  


• 
  

  severe constipation;

  
  


• 
  

  a blockage in your intestines;

  
  


• 
  

  a stomach or intestinal disorder; or

  
  


• 
  

  if you have recently had stomach or intestinal surgery.

  
  

FDA pregnancy category C. It is not known whether sevelamer will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether sevelamer passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take sevelamer?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Take sevelamer with meals. Do not crush, chew, or break the sevelamer tablet. Swallow the pill whole. Sevelamer tablets expand when they are wet, and breaking or crushing the pill may make it harder to swallow.

Sevelamer powder must be dissolved in water before you take it. The 0.8-gram packet should be mixed with at least 1 ounce (2 tablespoons) of water. The 2.4-gram packet should be mixed with at least 2 ounces (4 tablespoons) of water.

Stir the powder in water until it is completely dissolved. Drink all of this mixture right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

To be sure this medication is helping your condition and not causing harmful effects, your blood may need to be tested on a regular basis. Do not miss any scheduled appointments.

Sevelamer may be only part of a complete program of treatment that also includes a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you must eat or avoid to help control your condition.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Be sure to take the missed dose with food. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking sevelamer?

Avoid taking any other medicines within 1 hour before or 3 hours after you take sevelamer. Sevelamer can bind to other medications and make them less effective.

Do not take calcium or other mineral supplements without your doctor's advice. Use only the specific type of calcium or mineral supplement your doctor recommends.

Sevelamer side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using sevelamer and call your doctor at once if you have a serious side effect such as:

• 
  

  black, bloody, or tarry stools;

  
  


• 
  

  constipation that gets worse or does not clear up;

  
  


• 
  

  severe constipation with stomach pain; or

  
  


• 
  

  fever, chills, body aches, flu symptoms.

  
  

Less serious side effects may include:

• 
  

  nausea, vomiting, stomach pain, loss of appetite;

  
  


• 
  

  upset stomach, gas, bloating;

  
  


• 
  

  diarrhea, mild constipation;

  
  


• 
  

  tired feeling;

  
  


• 
  

  itching; or

  
  


• 
  

  joint pain.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Sevelamer Dosing Information

Usual Adult Dose for Hyperphosphatemia of Renal Failure:

Initial:
Dialysis patients not taking a phosphate binder:

Sevelamer carbonate:
800 mg to 1600 mg orally three times daily with each meal based on serum phosphorus level:
Phosphorus greater than 5.5 and less than 7.5 mg/dL = 800 mg
Phosphorus greater than or equal to 7.5 and less than 9.0 mg/dL = 1600 mg
Phosphorus greater than or equal to 9.0 mg/dL = 1600 mg

Sevelamer hydrochloride: Renagel(R):
Phosphorus greater than 5.5 and less than 7.5 mg/dL = One 800 mg tablet or two 400 mg tablets orally 3 times daily with meals
Phosphorus greater than or equal to 7.5 and less than 9.0 mg/dL = Two 800 mg tablets or three 400 mg tablets orally 3 times daily with meals
Phosphorus greater than or equal to 9.0 mg/dL = Two 800 mg tablets or four 400 mg tablets orally 3 times daily with meals

Patients switching from calcium acetate to sevelamer:

Sevelamer carbonate: For each calcium acetate 667 mg tablet used per meal, give sevelamer carbonate 800 mg per meal.

Sevelamer hydrochloride: Renagel(R):
One calcium acetate 667 mg tablet per meal: Substitute one sevelamer hydrochloride 800 mg or two sevelamer hydrochloride 400 mg tablets per meal.
Two calcium acetate 667 tablets mg per meal: Substitute two sevelamer hydrochloride 800 mg or three sevelamer hydrochloride 400 mg tablets per meal.
Three calcium acetate 667 tablets mg per meal: Substitute three sevelamer hydrochloride 800 mg or five sevelamer hydrochloride 400 mg tablets per meal.

Patients switching from sevelamer hydrochloride to sevelamer carbonate: Dosage should be prescribed on a gram per gram basis.

Maximum daily dose studied for sevelamer hydrochloride is 13,000 mg and for carbonate is 14,000 mg.

Usual Pediatric Dose for Hyperphosphatemia of Renal Failure:

In a small pilot study of 17 pediatric patients aged 11.8 plus or minus 3.7 years on hemodialysis (n=3) or peritoneal dialysis (n=14), initial doses of 121 plus or minus 50 mg/kg/day (4.5 plus or minus 5 g/day) were used. Doses were adjusted based on the serum phosphorus with final doses of 163 plus or minus 46 mg/kg (6.7 plus or minus 2.4 gm/day) without any adverse effects (Mahdavi, 2003). In a study of 18 patients aged 0.9 to 18 years with chronic kidney disease, a mean dose of 140 plus or minus 86 mg/kg/day (5.38 plus or minus 3.24 g/day) resulted in good phosphorus control with minimal adverse effects. Initial doses were based on prior phosphate binder dose and were adjusted based on the serum phosphorus (Pieper, 2006).

What other drugs will affect sevelamer?

Tell your doctor about all other medicines you use, especially:

• 
  

  ciprofloxacin (Cipro);

  
  


• 
  

  levothyroxine (Synthroid, Levothroid, Levoxyl);

  
  


• 
  

  a heart rhythm medication; or

  
  


• 
  

  a seizure medication.

  
  

This list is not complete and other drugs may interact with sevelamer. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More sevelamer resources

• Sevelamer Side Effects (in more detail)
• Sevelamer Use in Pregnancy & Breastfeeding
• Sevelamer Drug Interactions
• Sevelamer Support Group
• 1 Review for Sevelamer - Add your own review/rating

• sevelamer Advanced Consumer (Micromedex) - Includes Dosage Information


• Sevelamer Professional Patient Advice (Wolters Kluwer)


• Sevelamer Monograph (AHFS DI)


• Sevelamer MedFacts Consumer Leaflet (Wolters Kluwer)


• Renagel Prescribing Information (FDA)


• Renagel Consumer Overview


• Renvela Prescribing Information (FDA)


• Renvela Consumer Overview

Compare sevelamer with other medications

• Hyperphosphatemia of Renal Failure

Where can I get more information?

• Your pharmacist can provide more information about sevelamer.

See also: sevelamer side effects (in more detail)

Sertraline

Pronunciation: SER-tra-leen
Generic Name: Sertraline
Brand Name: Zoloft

Antidepressants may increase the risk of suicidal thoughts or actions in children, teenagers, and young adults. However, depression and certain other mental problems may also increase the risk of suicide. Talk with the patient's doctor to be sure that the benefits of using Sertraline outweigh the risks.

Family and caregivers must closely watch patients who take Sertraline. It is important to keep in close contact with the patient's doctor. Tell the doctor right away if the patient has symptoms like worsened depression, suicidal thoughts, or changes in behavior. Discuss any questions with the patient's doctor.

Sertraline is used for:

Treating depression or obsessive-compulsive disorder (OCD). It may be used to treat panic disorder or posttraumatic stress disorder (PTSD). It may also be used to treat premenstrual dysphoric disorder (PMDD; a severe form of premenstrual syndrome) or social anxiety disorder. It may also be used for other conditions as determined by your doctor.

Sertraline is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems.

Do NOT use Sertraline if:

• you are allergic to any ingredient in Sertraline


• you are taking or have taken linezolid, methylene blue, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine, selegiline), or St. John's wort within the last 14 days


• you are taking astemizole, a fenfluramine derivative (eg, dexfenfluramine), nefazodone, pimozide, serotonin-norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine, venlafaxine), sibutramine, other SSRIs (eg, citalopram, fluoxetine), terfenadine, thioridazine, or tryptophan

Contact your doctor or health care provider right away if any of these apply to you.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Before using Sertraline:

Some medical conditions may interact with Sertraline. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse


• if you have a history of seizures, heart problems, liver problems, stomach or bowel bleeding, or metabolism problems


• if you are dehydrated, have low blood sodium levels, or drink alcohol


• if you will be having electroconvulsive therapy (ECT)

Some MEDICINES MAY INTERACT with Sertraline. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Anorexiants (eg, phentermine), bupropion, fenfluramine derivatives (eg, dexfenfluramine), fentanyl, linezolid, MAOIs (eg, phenelzine, selegiline), meperidine, methylene blue, metoclopramide, nefazodone, serotonin 5-HT₁ receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, duloxetine, venlafaxine), other SSRIs (eg, citalopram, fluoxetine), St. John's wort, trazodone, or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur


• Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased


• Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of high or low blood sodium levels may be increased


• Tramadol because the risk of seizures may be increased


• Astemizole , phenothiazines (eg, chlorpromazine, thioridazine), or terfenadine because severe heart problems, including irregular heartbeat, may occur


• Carbamazepine or cyproheptadine because they may decrease Sertraline's effectiveness


• Aripiprazole, beta-blockers (eg, propanolol), clozapine, digoxin, flecainide, lithium, phenytoin, pimozide, propafenone, risperidone, tricyclic antidepressants (eg, amitriptyline), or valproate (eg, valproic acid) because the risk of their side effects may be increased by Sertraline


• Tamoxifen because its effectiveness may be decreased by Sertraline

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sertraline may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sertraline:

Use Sertraline as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Sertraline comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Sertraline refilled.


• Take Sertraline by mouth with or without food.


• Taking Sertraline at the same time each day will help you remember to take it.


• Continue to take Sertraline even if you feel well. Do not miss any doses.


• Do not suddenly stop taking Sertraline without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, confusion, headache, trouble sleeping, or unusual tiredness. You will be closely monitored when you start Sertraline and whenever a change in dose is made.


• If you miss a dose of Sertraline, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Sertraline.

Important safety information:

• Sertraline may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Sertraline with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol while you are taking Sertraline.


• Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking Sertraline; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, change your dose, or use Sertraline for longer than prescribed without checking with your doctor.


• Children and teenagers who take Sertraline may be at increased risk for suicidal thoughts or actions. Adults may also be affected. The risk may be greater in patients who have had suicidal thoughts or actions in the past. The risk may also be greater in patients who have had bipolar (manic-depressive) illness, or if their family members have had it. Watch patients who take Sertraline closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.


• If your doctor tells you to stop taking Sertraline, you will need to wait for several weeks before beginning to take certain other medicines (eg, MAOIs, nefazodone). Ask your doctor when you should start to take your new medicines after you have stopped taking Sertraline.


• Sertraline may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.


• Serotonin syndrome is a possibly fatal syndrome that can be caused by Sertraline. Your risk may be greater if you take Sertraline with certain other medicines (eg, "triptans," MAOIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.


• Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Sertraline. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.


• Sertraline may interfere with certain lab tests, including certain urine tests for benzodiazepines. Be sure your doctor and lab personnel know you are taking Sertraline.


• Caution is advised when using Sertraline in the ELDERLY; they may be more sensitive to its effects, especially low blood sodium levels.


• Caution is advised when using Sertraline in CHILDREN; they may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.


• Sertraline should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.


• Sertraline may cause weight changes. CHILDREN and teenagers may need regular weight and growth checks while they take Sertraline.


• PREGNANCY and BREAST-FEEDING: Sertraline may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Sertraline while you are pregnant. It is not known if Sertraline is found in breast milk. If you are or will be breast-feeding while you use Sertraline, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Sertraline:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; constipation; decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; increased sweating; loss of appetite; nausea; nervousness; stomach upset; tiredness; trouble sleeping; vomiting; weight loss.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; black or bloody stools; chest pain; confusion; decreased bladder control; decreased concentration; decreased coordination; exaggerated reflexes; fainting; fast or irregular heartbeat; fever; hallucinations; memory loss; new or worsening agitation, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; persistent or severe ringing in the ears; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety or trouble sleeping; severe or persistent headache; stomach pain; suicidal thoughts or attempts; tremor; unusual bruising or bleeding; unusual or severe mental or mood changes; unusual weakness; vision changes; worsening of depression.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Sertraline side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; fainting; fast, slow, or irregular heartbeat; hair loss; hallucinations; seizures; severe or persistent diarrhea, dizziness, drowsiness, nausea, or vomiting; tremor.

Proper storage of Sertraline:

Store Sertraline at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Sertraline out of the reach of children and away from pets.

General information:

• If you have any questions about Sertraline, please talk with your doctor, pharmacist, or other health care provider.


• Sertraline is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Sertraline. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sertraline resources

• Sertraline Side Effects (in more detail)
• Sertraline Dosage
• Sertraline Use in Pregnancy & Breastfeeding
• Drug Images
• Sertraline Drug Interactions
• Sertraline Support Group
• 397 Reviews for Sertraline - Add your own review/rating

• Sertraline Prescribing Information (FDA)


• sertraline Advanced Consumer (Micromedex) - Includes Dosage Information


• Sertraline Hydrochloride Monograph (AHFS DI)


• Zoloft Prescribing Information (FDA)


• Zoloft Consumer Overview

Compare Sertraline with other medications

• Anxiety and Stress
• Bipolar Disorder
• Body Dysmorphic Disorder
• Depression
• Dysautonomia
• Dysthymia
• Generalized Anxiety Disorder
• Obsessive Compulsive Disorder
• Panic Disorder
• Post Traumatic Stress Disorder
• Postpartum Depression
• Premenstrual Dysphoric Disorder
• Social Anxiety Disorder
• Trichotillomania
• Vulvodynia

silodosin

Generic Name: silodosin (SIL oh DOE sin)

Brand Names: Rapaflo

What is silodosin?

Silodosin is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Silodosin helps relax the muscles in the prostate and bladder neck, making it easier to urinate.

Silodosin is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

Silodosin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about silodosin?

You should not take silodosin if you have severe kidney or liver disease, or if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal), itraconazole (Sporanox), or ritonavir (Norvir).

Do not take silodosin with other similar medicines such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), or terazosin (Hytrin).

Silodosin may cause dizziness or fainting, especially when you first start taking it. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Silodosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using silodosin before surgery unless your surgeon tells you to.

There are many other drugs that can interact with silodosin. Tell your doctor about all medications you use.

What should I discuss with my health care provider before taking silodosin?

You should not take silodosin if you are allergic to it, or if you have:

• 
  

  severe kidney disease;

  
  


• 
  

  severe liver disease; or

  
  


• 
  

  if you are also using ketoconazole (Extina, Ketozole, Nizoral, Xolegal), itraconazole (Sporanox), or ritonavir (Norvir).

  
  

Do not take silodosin with other similar medicines such as alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), tamsulosin (Flomax), or terazosin (Hytrin).

If you have liver or kidney disease or a history of prostate cancer, you may need a silodosin dose adjustment or special tests to safely take this medication.

Silodosin can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medication. Do not stop using silodosin before surgery unless your surgeon tells you to.

Although this medication is not for use in women, silodosin is not expected to harm an unborn baby. If you are a woman using this medication, tell your doctor if you are pregnant or breast-feeding. Silodosin is not for use in children.

How should I take silodosin?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Silodosin is usually taken once daily with a meal. Silodosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it. Call your doctor if you have severe dizziness or feel like you might pass out.

You may feel very dizzy when you first wake up. Be careful when standing or sitting up from a lying position.

Your blood pressure and prostate will need to be checked often. Visit your doctor regularly.

Some things can cause your blood pressure to get too low. This includes vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.

Store at room temperature away from moisture, heat, and light.

See also: Silodosin dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme dizziness or fainting.

What should I avoid while taking silodosin?

Silodosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of silodosin.

Silodosin side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using silodosin and call your doctor at once if you have a serious side effect such as:

• 
  

  feeling like you might pass out; or

  
  


• penis erection that is painful or lasts 4 hours or longer.

Less serious side effects may include:

• 
  

  mild dizziness;

  
  


• 
  

  headache;

  
  


• 
  

  diarrhea;

  
  


• 
  

  abnormal ejaculation; or

  
  


• 
  

  runny or stuffy nose, sore throat.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Silodosin Dosing Information

Usual Adult Dose for Benign Prostatic Hyperplasia:

8 mg orally once a day with a meal

What other drugs will affect silodosin?

Tell your doctor about all other medications you use, especially:

• 
  

  conivaptan (Vaprisol);

  
  


• 
  

  imatinib (Gleevec);

  
  


• 
  

  isoniazid (for treating tuberculosis);

  
  


• 
  

  quinidine (Quin-G);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), or telithromycin (Ketek);

  
  


• 
  

  an antidepressant such as nefazodone;

  
  


• 
  

  antifungal medication such as clotrimazole (Mycelex Troche) or voriconazole (Vfend);

  
  


• 
  

  erectile dysfunction medicine such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);

  
  


• 
  

  heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nicardipine (Cardene), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;

  
  


• 
  

  HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), fosamprenavir (Lexiva), indinavir (Crixivan), or nelfinavir (Viracept), saquinavir (Invirase); or

  
  


• 
  

  medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf).

  
  

This list is not complete and there are many other drugs that can interact with silodosin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More silodosin resources

• Silodosin Side Effects (in more detail)
• Silodosin Dosage
• Silodosin Use in Pregnancy & Breastfeeding
• Silodosin Drug Interactions
• Silodosin Support Group
• 29 Reviews for Silodosin - Add your own review/rating

• silodosin Advanced Consumer (Micromedex) - Includes Dosage Information


• Silodosin Professional Patient Advice (Wolters Kluwer)


• Silodosin MedFacts Consumer Leaflet (Wolters Kluwer)


• Silodosin Monograph (AHFS DI)


• Rapaflo Prescribing Information (FDA)


• Rapaflo Consumer Overview

Compare silodosin with other medications

• Benign Prostatic Hyperplasia

Where can I get more information?

• Your pharmacist can provide more information about silodosin.

See also: silodosin side effects (in more detail)