SAStid Topical

Generic Name: salicylic acid and sulfur (Topical route)

sal-i-SIL-ik AS-id, SUL-fur

Commonly used brand name(s)

In the U.S.

• SAStid

In Canada

• Fostex Cream


• Night Cast R

Available Dosage Forms:

• Liquid


• Lotion


• Cream


• Soap


• Bar


• Ointment


• Shampoo

Therapeutic Class: Antiacne Keratolytic

Pharmacologic Class: NSAID

Chemical Class: Salicylate, Non-Aspirin

Uses For SAStid

Salicylic acid and sulfur combination is used to treat acne and other skin disorders and dandruff and other scalp disorders, such as seborrheic dermatitis.

This medicine is available without a prescription.

Before Using SAStid

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Young children may be at increased risk of unwanted effects because of increased absorption of salicylic acid through the skin. Products containing salicylic acid should not be applied to large areas of the body or used for long periods of time in infants and children.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of salicylic acid and sulfur combination in the elderly with use in other age groups.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abciximab


• Argatroban


• Bivalirudin


• Cilostazol


• Citalopram


• Clovoxamine


• Dabigatran Etexilate


• Dipyridamole


• Escitalopram


• Femoxetine


• Flesinoxan


• Fluoxetine


• Fluvoxamine


• Fondaparinux


• Heparin


• Lepirudin


• Nefazodone


• Paroxetine


• Protein C


• Rivaroxaban


• Sertraline


• Sibutramine


• Ticlopidine


• Tirofiban


• Vilazodone


• Zimeldine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Anisindione


• Ardeparin


• Azilsartan Medoxomil


• Azosemide


• Bemetizide


• Bendroflumethiazide


• Benzthiazide


• Bumetanide


• Buthiazide


• Candesartan Cilexetil


• Certoparin


• Chlorothiazide


• Chlorthalidone


• Clopamide


• Cyclopenthiazide


• Dalteparin


• Danaparoid


• Dicumarol


• Enoxaparin


• Eprosartan


• Ethacrynic Acid


• Furosemide


• Hydrochlorothiazide


• Hydroflumethiazide


• Indapamide


• Irbesartan


• Losartan


• Methyclothiazide


• Metolazone


• Nadroparin


• Olmesartan Medoxomil


• Parnaparin


• Phenindione


• Phenprocoumon


• Piretanide


• Polythiazide


• Probenecid


• Reviparin


• Tamarind


• Tasosartan


• Telmisartan


• Tinzaparin


• Torsemide


• Trichlormethiazide


• Valsartan


• Warfarin


• Xipamide

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of salicylic acid and sulfur

This section provides information on the proper use of a number of products that contain salicylic acid and sulfur. It may not be specific to SAStid. Please read with care.

Use this medicine only as directed. Do not use more of it and do not use it more often than recommended on the label, unless otherwise directed by your doctor.

Immediately after using this medicine, wash your hands to remove any medicine that may be on them.

Keep this medicine away from the eyes. If you should accidentally get some in your eyes, flush them thoroughly with water.

To use the skin cleansing lotion:

• After wetting the skin, apply this medicine with your fingertips or a wet sponge and rub in gently to work up a lather. Then rinse thoroughly and pat dry.

To use the shampoo or bar as a shampoo:

• Wet the hair and scalp with lukewarm water. Then apply enough medicine to work up a lather and rub into the scalp. Continue rubbing the lather into the scalp for several minutes or allow it to remain on the scalp for about 5 minutes, depending on the product being used, then rinse. Apply the medicine again and rinse thoroughly.

To use the bar as a soap:

• After wetting the skin, use this medicine to wash the face and other affected areas. Then rinse thoroughly and pat dry.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For acne or oily skin:
  
  • For bar dosage form:
    
    • Adults and children—Use on the affected skin two or three times a day.
    
    
  
  
  • For cleansing lotion dosage form:
    
    • Adults and children—Use on wet skin one to three times a day. Rub lather into skin for one minute then rinse.
    
    
  
  


• For dandruff and seborrheic dermatitis of the scalp:
  
  • For bar and shampoo dosage forms:
    
    • Adults and children—Use on the scalp once a day at least two times a week or as directed by doctor. May be used each day if needed.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using SAStid

When using salicylic acid and sulfur combination medicine, do not use any of the following preparations on the same affected area as this medicine, unless otherwise directed by your doctor:

• Abrasive soaps or cleansers


• Alcohol-containing preparations


• Any other topical acne preparation or preparation containing a peeling agent (for example, benzoyl peroxide, resorcinol, or tretinoin [vitamin A acid])


• Cosmetics or soaps that dry the skin


• Medicated cosmetics


• Other topical medicine for the skin

To use any of the above preparations on the same affected area as salicylic acid and sulfur combination medicine may cause severe irritation of the skin.

Do not use any topical mercury-containing preparation, such as ammoniated mercury ointment, on the same affected area as this medicine . To do so may cause a foul odor, may be irritating to the skin, and may stain the skin black. If you have any questions about this, check with your health care professional.

Taking large doses of aspirin or other salicylates (including diflunisal) while using topical salicylic acid (contained in this medicine) may lead to overdose. If you have any questions about this, check with your health care professional.

SAStid Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Skin irritation not present before use of this medicine

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Redness and peeling of skin (may occur after a few days)


• unusual dryness of skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: SAStid Topical side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More SAStid Topical resources

• SAStid Topical Side Effects (in more detail)
• SAStid Topical Use in Pregnancy & Breastfeeding
• SAStid Topical Drug Interactions
• SAStid Topical Support Group
• 0 Reviews for SAStid Topical - Add your own review/rating

Compare SAStid Topical with other medications

• Acne
• Dandruff

scorpion (centruroides) immune f(ab)2 Intravenous

SKOR-pee-on SEN-troo-roy-deez i-MUNE fab-too

Commonly used brand name(s)

In the U.S.

• Anascorp

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antivenom

Uses For scorpion (centruroides) immune f(ab)2

Scorpion (Centruroides) immune F(ab)2 injection is used to treat scorpion stings. A scorpion sting may cause abnormal eye movements, increased watering of the mouth, loss of muscle control, shortness of breath, slurred speech, troubled breathing, or vomiting. scorpion (centruroides) immune f(ab)2 is made from horse proteins that have been immunized with the scorpion’s venom.

scorpion (centruroides) immune f(ab)2 is to be given only by or under the direct supervision of a doctor.

Before Using scorpion (centruroides) immune f(ab)2

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For scorpion (centruroides) immune f(ab)2, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to scorpion (centruroides) immune f(ab)2 or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of scorpion (Centruroides) immune F(ab)2 injection in children.

Geriatric

Although appropriate studies on the relationship of age to the effects of scorpion (Centruroides) immune F(ab)2 injection have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of scorpion (centruroides) immune f(ab)2. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to horse protein or


• Prior use of an antivenom containing horse protein—Use with caution. May increase the likelihood for an allergic reaction.

Proper Use of scorpion (centruroides) immune f(ab)2

A nurse or other trained health professional will give you scorpion (centruroides) immune f(ab)2 in a hospital. scorpion (centruroides) immune f(ab)2 is given through a needle placed in one of your veins.

Precautions While Using scorpion (centruroides) immune f(ab)2

Your doctor will check your or your child's progress closely while you are receiving scorpion (centruroides) immune f(ab)2. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

scorpion (centruroides) immune f(ab)2 may cause serious types of allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, or mouth while you are receiving scorpion (centruroides) immune f(ab)2.

Call your doctor or the emergency department right away if you or your child have a delayed allergic reaction or serum sickness, which may occur up to 14 days after receiving scorpion (centruroides) immune f(ab)2. The symptoms may include a rash, itching skin, fever, general feeling of discomfort or illness, joint or muscle pain, unusual tiredness or weakness, or swollen, painful, or tender lymph glands in the neck, armpit, or groin.

scorpion (centruroides) immune f(ab)2 is made from horse blood. Some horse blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made from horse blood has been greatly reduced in recent years. This is the result of required testing of horses for certain viruses, and testing during the making of these medicines. Although the risk is low, talk with your doctor if you have concerns.

scorpion (centruroides) immune f(ab)2 Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

• Chest pain


• confusion


• cough


• dizziness


• fast heartbeat


• feeling of discomfort


• fever or chills


• inflammation of the joints


• itching


• muscle aches


• rash


• shakiness and unsteady walk


• shortness of breath


• sneezing


• sore throat


• swelling of the eye


• swollen lymph glands


• tightness in the chest


• troubled breathing


• unsteadiness, trembling, or other problems with muscle control or coordination


• weakness


• wheezing

Incidence not known

• Fast, irregular, pounding, or racing heartbeat or pulse

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Diarrhea


• difficulty with moving


• headache


• joint pain


• muscle cramping


• muscle pains or stiffness


• nausea


• runny nose


• swollen joints


• unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness


• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Scheinpharm Amoxicillin

Generic Name: amoxicillin (Oral route)

a-mox-i-SIL-in

Commonly used brand name(s)

In the U.S.

• Amoxicot


• Amoxil


• DisperMox


• Moxatag


• Moxilin


• Trimox

In Canada

• Amoxil Pediatric


• Apo-Amoxi


• Apo-Amoxi Sugar-Free


• Gen-Amoxicillin


• Med Amoxicillin


• Novamoxin


• Novamoxin Reduced Sugar


• Nu-Amoxi


• Riva-Amoxicillin


• Scheinpharm Amoxicillin


• Zimamox

Available Dosage Forms:

• Tablet


• Tablet, Chewable


• Tablet for Suspension


• Powder for Suspension


• Tablet, Extended Release


• Capsule

Therapeutic Class: Antibiotic

Pharmacologic Class: Penicillin, Aminopenicillin

Uses For Scheinpharm Amoxicillin

Amoxicillin is used to treat bacterial infections in many different parts of the body. It is also used with other medicines (e.g., clarithromycin, lansoprazole) to treat H. pylori infection and duodenal ulcers.

Amoxicillin belongs to the group of medicines known as penicillin antibiotics. It works by killing the bacteria and preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Before Using Scheinpharm Amoxicillin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of amoxicillin in children. However, newborns and infants 3 months of age and younger have incompletely developed kidney functions, which may need a lower dose of this medicine.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amoxicillin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving amoxicillin.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Methotrexate


• Venlafaxine

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Acenocoumarol


• Desogestrel


• Dienogest


• Drospirenone


• Estradiol Cypionate


• Estradiol Valerate


• Ethinyl Estradiol


• Ethynodiol Diacetate


• Etonogestrel


• Khat


• Levonorgestrel


• Medroxyprogesterone Acetate


• Mestranol


• Norelgestromin


• Norethindrone


• Norgestimate


• Norgestrel


• Probenecid


• Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Allergy to penicillins or cephalosporin antibiotics (e.g., cefaclor, cefadroxil, cephalexin, Ceftin®, or Keflex®) or


• Mononucleosis (viral infection)—Should not be used in patients with these conditions.

• Kidney disease, severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

• Phenylketonuria (PKU)—The chewable tablet contains phenylalanine, which can make this condition worse.

Proper Use of amoxicillin

This section provides information on the proper use of a number of products that contain amoxicillin. It may not be specific to Scheinpharm Amoxicillin. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

You may take this medicine with or without food.

For patients using the oral liquid:

• Shake the bottle well before each use. Measure the dose with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.


• You may mix the oral liquid with a baby formula, milk, fruit juice, water, ginger ale, or another cold drink. Be sure the child drinks all of the mixture immediately.

Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage forms (capsules, powder for suspension, and tablets):
  
  • For bacterial infections:
    
    • Adults, teenagers, and children weighing 40 kilograms (kg) or more—250 to 500 milligrams (mg) every 8 hours, or 500 to 875 mg every 12 hours.
    
    
    • Children and infants older than 3 months of age weighing less than 40 kg—Dose is based on body weight and must be determined by your doctor. The usual dose is 20 to 40 milligrams (mg) per kilogram (kg) of body weight per day, divided and given every 8 hours, or 25 to 45 mg per kg of body weight per day, divided and given every 12 hours.
    
    
    • Infants 3 months of age and younger—Dose is based on body weight and must be determined by your doctor. The usual dose is 30 mg per kg of body weight per day, divided and given every 12 hours.
    
    
  
  
  • For treatment of gonorrhea:
    
    • Adults, teenagers, and children weighing 40 kilograms (kg) or more—3-grams (g) taken as a single dose.
    
    
    • Children 2 years of age and older weighing less than 40 kg—Dose is based on body weight and must be determined by your doctor. The usual dose is 50 milligrams (mg) per kilogram (kg) of body weight per day, combined with 25 mg per kg of probenecid, taken as a single dose.
    
    
    • Children younger than 2 years of age—Use is not recommended.
    
    
  
  
  • For treatment of H. pylori infection:
    
    • Adults—
      
      • Dual therapy: 1000 milligrams (mg) of amoxicillin and 30 mg of lansoprazole, each given three times a day (every 8 hours) for 14 days.
      
      
      • Triple therapy: 1000 mg of amoxicillin, 500 mg of clarithromycin, and 30 mg of lansoprazole, all given two times a day (every 12 hours) for 14 days.
      
      
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

You may store the oral liquid in the refrigerator. Throw away any unused medicine after 14 days. Do not freeze.

Precautions While Using Scheinpharm Amoxicillin

If your or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.

This medicine may cause a serious allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a skin rash; itching; shortness of breath; trouble with breathing; trouble with swallowing; or any swelling of your hands, face, mouth, or throat after you or your child receive this medicine.

Amoxicillin may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop taking this medicine. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Before you have any medical tests, tell the doctor in charge that you or your child are taking this medicine. The results of some tests may be affected by this medicine.

In some young patients, tooth discoloration may occur while using this medicine. The teeth may appear to have brown, yellow, or gray stains. To help prevent this, brush and floss your teeth regularly or have a dentist clean your teeth.

Birth control pills may not work while you are using this medicine. To keep from getting pregnant, use another form of birth control along with your birth control pills. Other forms include a condom, a diaphragm, or a contraceptive foam or jelly.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Scheinpharm Amoxicillin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Abdominal or stomach cramps or tenderness


• back, leg, or stomach pains


• black, tarry stools


• bleeding gums


• blistering, peeling, or loosening of the skin


• bloating


• blood in the urine


• bloody nose


• chest pain


• chills


• clay-colored stools


• cough


• dark urine


• diarrhea


• diarrhea, watery and severe, which may also be bloody


• difficulty with breathing


• difficulty with swallowing


• dizziness


• fast heartbeat


• feeling of discomfort


• fever


• general body swelling


• headache


• heavier menstrual periods


• hives or welts


• increased thirst


• inflammation of the joints


• itching


• joint or muscle pain


• loss of appetite


• muscle aches


• nausea or vomiting


• nosebleeds


• pain


• pain in the lower back


• pain or burning while urinating


• painful or difficult urination


• pale skin


• pinpoint red spots on the skin


• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue


• rash


• red, irritated eyes


• redness, soreness, or itching skin


• shortness of breath


• sore throat


• sores, ulcers, or white spots in the mouth or on the lips


• sores, welting, or blisters


• sudden decrease in the amount of urine


• swollen, lymph glands


• tenderness


• tightness in the chest


• unpleasant breath odor


• unusual bleeding or bruising


• unusual tiredness or weakness


• unusual weight loss


• vomiting of blood


• watery or bloody diarrhea


• wheezing


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Bad, unusual, or unpleasant (after) taste


• change in taste

Incidence not known

• Agitation


• black, hairy tongue


• changes in behavior


• confusion


• convulsions


• discoloration of the tooth (brown, yellow, or gray staining)


• dizziness


• sleeplessness


• trouble with sleeping


• unable to sleep


• white patches in the mouth or throat or on the tongue


• white patches with diaper rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Scot-Tussin DM Cough Chasers

Generic Name: dextromethorphan (dex troe meth OR fan)

Brand Names: Babee Cof, Benylin DM Pediatric, Buckley's Mixture Cough Suppressant, Buckleys Mixture, Creo-Terpin, Creomulsion, Delsym, Delsym 12 Hour Cough Relief, Delsym 12 Hour Cough Relief for Children & Adults, DexAlone, Elixsure Cough, Hold DM, Pediacare, Robitussin CoughGels, Robitussin Honey Cough, Robitussin Maximum Strength, Robitussin Pediatric Cough Suppressant, Scot-Tussin Diabetic, Scot-Tussin DM Cough Chasers, Silphen DM, St. Joseph Cough Suppressant, Sucrets DM Cough, Theraflu Thin Strips Cough, Triaminic Long Acting Cough, Triaminic Softchew, Vicks 44 Cough Relief

What is Scot-Tussin DM Cough Chasers (dextromethorphan)?

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Dextromethorphan is used to treat a cough.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Scot-Tussin DM Cough Chasers (dextromethorphan)?

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use dextromethorphan if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan. Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

What should I discuss with my healthcare provider before taking Scot-Tussin DM Cough Chasers (dextromethorphan)?

Do not use dextromethorphan if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take dextromethorphan before the MAO inhibitor has cleared from your body.

Ask a doctor or pharmacist about using this medicine if you have emphysema or chronic bronchitis.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough medicine may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take Scot-Tussin DM Cough Chasers (dextromethorphan)?

Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cough medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving cough or cold medicine to a child. Death can occur from the misuse of cough or cold medicine in very young children.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Allow the dextromethorphan lozenge or disintegrating strip to dissolve in your mouth.

Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cough medicine within the past few days.

Store dextromethorphan at room temperature, away from heat, light, and moisture.

What happens if I miss a dose?

Since cough medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous.

What should I avoid while taking Scot-Tussin DM Cough Chasers (dextromethorphan)?

Avoid drinking alcohol. It can increase some of the side effects of dextromethorphan. This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with cough medicine can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, or allergy medication without first asking your doctor or pharmacist. Dextromethorphan is contained in many combination medicines available over the counter. If you take certain products together you may accidentally take too much of this medicine. Read the label of any other medicine you are using to see if it contains dextromethorphan.

Scot-Tussin DM Cough Chasers (dextromethorphan) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using dextromethorphan and call your doctor at once if you have any of these serious side effects:

• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  confusion, hallucinations; or

  
  


• 
  

  slow, shallow breathing.

  
  

Less serious side effects are more likely, such as stomach upset.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Scot-Tussin DM Cough Chasers (dextromethorphan)?

Before taking dextromethorphan, tell your doctor if you are using any of the following drugs:

• 
  

  celecoxib (Celebrex);

  
  


• 
  

  cinacalcet (Sensipar);

  
  


• 
  

  darifenacin (Enablex);

  
  


• 
  

  imatinib (Gleevec);

  
  


• 
  

  quinidine (Quinaglute, Quinidex);

  
  


• 
  

  ranolazine (Ranexa)

  
  


• 
  

  ritonavir (Norvir);

  
  


• 
  

  sibutramine (Meridia);

  
  


• 
  

  terbinafine (Lamisil);

  
  


• 
  

  medicines to treat high blood pressure; or

  
  


• 
  

  antidepressant medications such as amitriptyline (Elavil, Etrafon), bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), paroxetine (Paxil), sertraline (Zoloft), and others.

  
  

This list is not complete and there may be other drugs that can interact with dextromethorphan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Scot-Tussin DM Cough Chasers resources

• Scot-Tussin DM Cough Chasers Side Effects (in more detail)
• Scot-Tussin DM Cough Chasers Use in Pregnancy & Breastfeeding
• Scot-Tussin DM Cough Chasers Drug Interactions
• 0 Reviews for Scot-Tussin DM Cough Chasers - Add your own review/rating

• Creo-Terpin Advanced Consumer (Micromedex) - Includes Dosage Information


• Delsym Extended-Release Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• DexAlone MedFacts Consumer Leaflet (Wolters Kluwer)


• Dextromethorphan Hydrobromide Monograph (AHFS DI)


• ElixSure Cough Gel Syrup MedFacts Consumer Leaflet (Wolters Kluwer)


• Robitussin Maximum Strength Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Triaminic Long Acting Cough Orally Disintegrating Strips MedFacts Consumer Leaflet (Wolters Kluwer)


• Tussin Pediatric Elixir MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Scot-Tussin DM Cough Chasers with other medications

• Cough

Where can I get more information?

• Your pharmacist can provide more information about dextromethorphan.

See also: Scot-Tussin DM Cough Chasers side effects (in more detail)

Scopace

Generic Name: atropine, homatropine, and scopolamine (Ophthalmic route)

Commonly used brand name(s)

In the U.S.

• AK-Dilate


• AK-Pentolate


• Altafrin


• Atropine Care


• Cyclogyl


• Cyclomydril


• Eye Cool


• Homatropaire


• Isopto Atropine


• Isopto Homatropine


• Isopto Hyoscine


• Mydfrin


• Mydral


• Mydriacyl


• Neofrin


• Neo-Synephrine


• Paremyd

In Canada

• Ak-Dilate


• Ak-Pentolate


• Atropine


• Atropine-Ak


• Atropine Eye Ointment


• Atropine Ointment


• Atropisol


• Minims Phenylephrine Hydrochloride

Available Dosage Forms:

• Ointment


• Solution

Uses For Scopace

Ophthalmic atropine, homatropine, and scopolamine are used to dilate (enlarge) the pupil of the eye. They are used before eye examinations, before and after eye surgery, and to treat certain eye conditions, such as uveitis or posterior synechiae.

These medicines are available only with your doctor's prescription.

Before Using Scopace

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Infants and young children and children with blond hair or blue eyes may be especially sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the chance of side effects during treatment . Children should use a lower strength of this medicine.

Geriatric

Elderly people are especially sensitive to the effects of atropine, homatropine, or scopolamine. This may increase the chance of side effects during treatment.

Pregnancy

Studies on effects in pregnancy have not been done in either humans or animals. However, these medicines may be absorbed into the body.

Breast Feeding

These medicines may be absorbed into the body. Atropine passes into the breast milk in very small amounts and may cause side effects, such as fast pulse, fever, or dry skin, in babies of nursing mothers using ophthalmic atropine. It is not known whether homatropine or scopolamine passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are using one of these medicines and who wish to breast-feed should discuss this with their doctor.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

• Brain damage (in children) or


• Down's syndrome (mongolism) (in children and adults) or


• Glaucoma or


• Other eye diseases or problems or


• Spastic paralysis (in children)—Use of ophthalmic atropine, homatropine, or scopolamine may make the condition worse.

Proper Use of atropine, homatropine, and scopolamine

This section provides information on the proper use of a number of products that contain atropine, homatropine, and scopolamine. It may not be specific to Scopace. Please read with care.

To use the ophthalmic solution (eye drops) form of this medicine:

• First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Drop the medicine into this space. Let go of the eyelid and gently close the eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye with your finger for 2 or 3 minutes to allow the medicine to be absorbed by the eye.


• Immediately after using the eye drops, wash your hands to remove any medicine that may be on them. If you are using the eye drops for an infant or child, be sure to wash his or her hands immediately afterwards also, and do not let any of the medicine get in his or her mouth. In addition, wipe off any medicine that may have accidentally gotten on the infant or child, including his or her face or eyelids.


• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed.

To use the ointment form of this medicine:

• First, wash your hands. Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space. A 1/3- to ½;-cm (approximately ⅛-inch in infants and young children and ¼-inch in older children and adults) strip of ointment is usually enough, unless you have been told by your doctor to use a different amount. Let go of the eyelid and gently close the eyes. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed by the eye.


• Immediately after using the eye ointment, wash your hands to remove any medicine that may be on them. If you are using the eye ointment for an infant or child, be sure to wash his or her hands immediately afterwards also, and do not let any of the medicine get in his or her mouth. In addition, wipe off any medicine that may have accidentally gotten on the infant or child, including his or her face or eyelids.


• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). After using the eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed.

Use this medicine only as directed. Do not use more of it and do not use it more often than your doctor ordered. To do so may increase the chance of too much medicine being absorbed into the body and the chance of side effects. This is especially important when this medicine is used in infants and children, since overdose is very dangerous in infants and children.

Dosing

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For atropine


• For ophthalmic ointment dosage form:
  
  • For uveitis:
    
    • Adults—Use a thin strip of the ointment in the eye one or two times a day.
    
    
    • Children—Use a thin strip of the ointment in the eye one to three times a day.
    
    
  
  
  • For eye examinations:
    
    • Adults—Use and dose must be determined by your doctor.
    
    
    • Children—Use a thin strip of the ointment in the eye three times a day for one to three days before the examination.
    
    
  
  


• For ophthalmic solution (eye drops) dosage form:
  
  • For uveitis:
    
    • Adults—Use one drop in the eye one or two times a day.
    
    
    • Children—Use one drop in the eye one to three times a day.
    
    
  
  
  • For eye examinations:
    
    • Adults—Use and dose must be determined by your doctor.
    
    
    • Children—Use one drop in the eye two times a day for one to three days before the examination.
    
    
  
  

• For homatropine


• For ophthalmic solution (eye drops) dosage form:
  
  • For uveitis:
    
    • Adults and children—Use 1 or 2 drops in the eye two or three times a day.
    
    
  
  
  • For eye examinations:
    
    • Adults—Use 1 or 2 drops in the eye. May be repeated every five to ten minutes for two or three doses.
    
    
    • Children—Use 1 or 2 drops in the eye every ten minutes for two or three doses.
    
    
  
  

• For scopolamine


• For ophthalmic solution (eye drops) dosage form:
  
  • For uveitis:
    
    • Adults and children—Use one drop in the eye up to four times a day.
    
    
  
  
  • For eye examinations:
    
    • Adults—Use one drop in the eye one hour before the examination.
    
    
    • Children—Use one drop in the eye two times a day for two days before the examination.
    
    
  
  
  • For posterior synechiae:
    
    • Adults—Use one drop in the eye every ten minutes for three doses.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  
  • For use before and after surgery:
    
    • Adults and children—Use one drop in the eye one to four times a day.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose of this medicine and your dosing schedule is:

• One dose a day—Apply the missed dose as soon as possible. However, if you do not remember the missed dose until the next day, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


• More than one dose a day—Apply the missed dose as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using Scopace

After you apply this medicine to your eyes:

• Your pupils will become unusually large and you will have blurring of vision, especially for close objects. Make sure your vision is clear before you drive, use machines, or do anything else that could be dangerous if you are not able to see well.


• Your eyes will become more sensitive to light than they are normally. Wear sunglasses to protect your eyes from sunlight and other bright lights.

These effects may continue for several days after you stop using this medicine. However, check with your doctor if they continue longer than:

• 14 days if you are using atropine.


• 3 days if you are using homatropine.


• 7 days if you are using scopolamine.

Scopace Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Symptoms of too much medicine being absorbed into the body

• Clumsiness or unsteadiness


• confusion or unusual behavior


• dryness of skin


• fast or irregular heartbeat


• fever


• flushing or redness of face


• seeing, hearing, or feeling things that are not there


• skin rash


• slurred speech


• swollen stomach in infants


• thirst or unusual dryness of mouth


• unusual drowsiness, tiredness, or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

• Blurred vision


• brief burning or stinging of the eyes


• eye irritation not present before use of this medicine


• increased sensitivity of eyes to light


• swelling of the eyelids

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

Scleromate

Pronunciation: MOR-yoo-ate
Generic Name: Morrhuate
Brand Name: Scleromate

Scleromate is used for:

Treating varicose veins.

Scleromate is a mixture of saturated and unsaturated fatty acids. It works by causing inflammation of the inside of the injected vein and creating a blood clot, which results in the destruction of the vein.

Do NOT use Scleromate if:

• you are allergic to any ingredient in Scleromate


• you have an infection of the blood, tuberculosis (TB), or any other infection


• you have a blood clot in the veins (deep vein thrombosis), blood problems, skin problems, a blockage in your blood vessels, inflammation of your veins, tumors, cancer, or varicose veins caused by unusual growths or tumors in your abdominal or pelvic area


• you have asthma, a severely overactive thyroid, or uncontrolled diabetes

Contact your doctor or health care provider right away if any of these apply to you.

Before using Scleromate:

Some medical conditions may interact with Scleromate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Scleromate. However, no specific interactions with Scleromate are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Scleromate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Scleromate:

Use Scleromate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Scleromate is usually administered as an injection at your doctor's office, hospital, or clinic.


• If Scleromate contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.


• If you miss a dose of Scleromate, contact your doctor.

Ask your health care provider any questions you may have about how to use Scleromate.

Important safety information:

• PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, discuss with your doctor the benefits and risks of using Scleromate during pregnancy. If you are or will be breast-feeding while you are using Scleromate, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Scleromate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Aching; burning, cramping, discoloration (light bronze color), or a sensation of stiffness around the injection area.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); pain, redness, or swelling around the injection site; skin ulceration.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Scleromate side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Scleromate:

Store Scleromate at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Scleromate out of the reach of children and away from pets.

General information:

• If you have any questions about Scleromate, please talk with your doctor, pharmacist, or other health care provider.


• Scleromate is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Scleromate. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Scleromate resources

• Scleromate Side Effects (in more detail)
• Scleromate Use in Pregnancy & Breastfeeding
• Scleromate Support Group
• 0 Reviews for Scleromate - Add your own review/rating

• Morrhuate Sodium Professional Patient Advice (Wolters Kluwer)

Compare Scleromate with other medications

• Varicose Veins

Sclerosol

Generic Name: Talc
Class: Sclerosing Agents
CAS Number: 14807-96-6

Introduction

Sclerosing agent;^{1 2} sterile, asbestos- and brucite-free, controlled-granule-size talc powder.¹

Uses for Sclerosol

Pleural Effusions

Sclerosis of pleural serosal surfaces (pleurodesis) to decrease the risk of malignant pleural effusion recurrence in symptomatic patients with advanced stages of metastatic tumors.^{1 2 3 4 5 6 7 8 9 10}

Safety and efficacy based on data from published literature.^{1 2 3 14}

Absence of reaccumulation of the effusion (determined by clinical examination or chest radiograph) reported in about 93% of patients with recurrent, symptomatic malignant pleural effusions.^{3 14}

Similar success rates with talc slurry or aerosol powder.³

May be at least as effective as intrapleural bleomycin,^{1 2 6 7 8 9 15 16 17} doxycycline,¹² mustine,^{2 11} or tetracycline^{2 10} (no longer commercially available as a parenteral formulation in the US) and more effective than therapeutic thoracentesis.^{1 2 4 11}

Sclerosol Dosage and Administration

Administration

Administer intrapleurally as a slurry instilled via a chest tube¹ or by aerosol during thoracoscopy or open thoracotomy.²

Intrapleural Instillation via Chest Tube

Preparation of Slurry

Prepare slurry in a laminar flow hood using aseptic technique.¹

Attach 16-gauge needle to a 60-mL Leur-Lok syringe and draw up 50 mL of 0.9% sodium chloride injection into the syringe.¹

Vent vial containing 5 g of talc with a needle; slowly inject syringe contents into the vial and swirl to disperse.¹

Continue swirling vial to prevent settling; draw up 25 mL of slurry into each of 2 60-mL syringes.¹

Draw up sufficient 0.9% sodium chloride injection into each syringe to total 50 mL; each syringe will contain a slurry of 2.5 g of talc per 50 mL of 0.9% sodium chloride injection.¹

Draw air into each syringe to the 60-mL mark to provide 10 mL of space for mixing prior to administration.¹

Appropriately label each syringe, including expiration date and time, identity of patient to receive the preparation, and the cautionary statements “For Pleurodesis Only–NOT FOR IV ADMINISTRATION” and “Shake Well Before Use.“ ¹

Use slurry within 12 hours of preparation.¹

Administration Procedure

Prior to administration, adequately drain the effusion from the pleural cavity.^{1 2} Success of treatment apparently is related to the completeness of pleural fluid drainage and to full reexpansion of the lung.^{1 2}

Completely and continuously agitate the slurry-containing syringes to disperse and avoid settlement of the talc.¹

Immediately prior to administration, vent the 10 mL of air (provided for mixing) from each syringe.¹

Attach the adapter and place a syringe tip on the adapter; maintain continuous agitation of the syringes.¹

Apply gentle pressure to syringe plunger to empty syringe contents through the chest tube into the chest cavity.¹

Flush the chest tube with 10–25 mL of 0.9% sodium chloride solution to ensure complete dose delivery; clamp the drainage tube.¹

Have the patient move from supine to alternating decubitus positions at 20- to 30-minute intervals over a period of about 2 hours to distribute the talc within the chest cavity;¹ however, recent evidence suggests that this step may not be necessary.¹

At the end of this period, unclamp the chest drainage tube and remove excess saline by routine continual external suction on the tube.¹

Intrapleural Aerosol

Administration Procedure

Prior to administration, adequately drain the effusion from the pleural cavity.^{1 2} Success of treatment apparently is related to the completeness of pleural fluid drainage and to full reexpansion of the lung.^{1 2}

Shake aerosol canister well before use; securely attach actuator button with delivery tube (15 or 25 cm) to canister valve stem.²

Insert delivery tube through the pleural trocar; avoid placing the distal end of the tube adjacent to lung parenchyma or directly against the chest wall.²

For optimal distribution, always maintain canister in an upright position.²

Firmly hold the delivery tube and pleural trocar together in one hand, and gently press the actuator button on the canister.²

While pointing the distal end of the delivery tube in several different directions, administer short bursts to distribute talc equally and extensively on all visceral and parietal pleural surfaces.²

Discard the canister and delivery tube after application.²

The duration of chest tube drainage following sclerosis is dictated by the clinical situation.²

Rate of Administration

Commercially available spray canister delivers talc at a rate of 0.4 g per second but is not considered to be a metered-dose delivery system; dose delivered depends on the extent and duration of manual compression of the actuator button.²

Dosage

Adults

Pleural Effusions

Intrapleural Instillation

5 g as slurry dispersed in 50–100 mL of 0.9% sodium chloride injection.¹

Optimal dose is unknown; 5 g was most frequently reported dose in published literature.¹

Intrapleural Aerosol

Usually 4–8 g (from 1–2 spray canisters) as a single dose.²

Special Populations

No special population dosage recommendations at this time.^{1 2}

Cautions for Sclerosol

Contraindications

• 
  

  No known contraindications.^{1 2}

  
  

Warnings/Precautions

General Precautions

Future Procedures

Prior to administration, consider the possible need for future diagnostic and therapeutic procedures involving the hemithorax.^{1 2} Sclerosis of pleural space may preclude subsequent diagnostic procedures of the pleura on the treated side and may complicate or preclude future ipsilateral lung resective surgery, including pneumonectomy for transplantation purposes.^{1 2}

Potentially Curable Malignancies

Talc has no known antineoplastic activity; do not use alone for potentially curable malignancies (e.g., a malignant effusion secondary to a potentially curable lymphoma) when systemic antineoplastic therapy would be more appropriate.^{1 2}

Pulmonary Complications

Acute pneumonitis and ARDS reported; 3 of 4 reports of ARDS occurred following relatively large dose (10 g) instilled intrapleurally via chest tube.^{1 2}

IV administration causes pulmonary hypertension and lung parenchymal disease; not reported following intrapleural administration.²

Inhaled talc associated with pulmonary diseases (e.g., silicosis or asbestos-like disease, chronic bronchitis, bronchogenic carcinoma, pleural plaques).²

Aerosol Canister Pressure

The contents of the aerosol canister are under pressure; do not puncture or use near heat or open flame.²

Specific Populations

Pregnancy

Category B.^{1 2}

Pediatric Use

Safety and efficacy not established in children <18 years of age.^{1 2}

Geriatric Use

Safety and efficacy in geriatric patients not specifically evaluated.^{1 2}

Estimated mean and median ages of patients receiving intrapleural talc slurry in clinical studies were 60 and 62 years, respectively.¹ Mean and median ages of patients receiving talc intrapleural aerosol were 50–62 years.²

Common Adverse Effects

Fever, pain.^{1 2}

Interactions for Sclerosol

Specific Drugs

Drug	Comments
Sclerosing agents	Unknown whether talc’s absorptive properties may diminish the effectiveness of subsequent therapy with a second sclerosing agent1 2

Sclerosol Pharmacokinetics

Absorption

Bioavailability

Extent of absorption after intrapleural administration not determined; integrity of the pleural surface may affect systemic exposure.^{1 2}

Special Populations

Systemic exposure may be increased when administered immediately following lung resection or biopsy.^{1 2}

Stability

Storage

Intrapleural

Powder

18–25°C.¹ Protect from sunlight.¹

Use slurry within 12 hours following preparation.¹

Aerosol

15–30°C.² Do not expose to temperatures >49°C (canister may rupture).² Avoid freezing.² Protect from sunlight.²

ActionsActions

• 
  

  Following intrapleural administration, talc induces inflammation that results in fibrosis and adherence of visceral to parietal pleura (pleurodesis), thereby obliterating the pleural space and reducing the chance of fluid reaccumulation.^{1 2 18 19 20}

  
  

Advice to Patients

• 
  

  Importance of describing the intrapleural procedure to patients prior to administration of talc.

  
  


• 
  

  Importance of informing patients of other important precautionary information. (See Cautions.)

  
  

Preparations

Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.

Talc

Routes	Dosage Forms	Strengths	Brand Names	Manufacturer
Intrapleural	Aerosol	4 g	Sclerosol Intrapleural Aerosol (with dichlorodifluoromethane [CFC-12] propellants)	Bryan
	Powder	5 g	Sterile Talc Powder	Bryan

Disclaimer

This report on medications is for your information only, and is not considered individual patient advice. Because of the changing nature of drug information, please consult your physician or pharmacist about specific clinical use.

The American Society of Health-System Pharmacists, Inc. and Drugs.com represent that the information provided hereunder was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The American Society of Health-System Pharmacists, Inc. and Drugs.com make no representations or warranties, express or implied, including, but not limited to, any implied warranty of merchantability and/or fitness for a particular purpose, with respect to such information and specifically disclaims all such warranties. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the information is provided for informational purposes only. The entire monograph for a drug should be reviewed for a thorough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc. and Drugs.com do not endorse or recommend the use of any drug. The information is not a substitute for medical care.

AHFS Drug Information. © Copyright, 1959-2011, Selected Revisions October 2005. American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland 20814.

References

1. Bryan Corporation. Sterile talc powder prescribing information. Woburn, MA; undated.

2. Bryan Corporation. Sclerosol (sterile talc powder) intrapleural aerosol prescribing information. Woburn, MA; undated.

3. American Thoracic Society. Management of malignant pleural effusions. Am J Respir Crit Care Med. 2000; 162:1987-2001. [PubMed 11069845]

4. Sorensen PG, Svendsen TL, Enk B. Treatment of malignant pleural effusion with drainage, with and without instillation of talc. Eur J Respir Dis. 1984; 65:131-5. [PubMed 6365578]

5. Aelony Y, King R, Boutin C. Thoracoscopic talc poudrage pleurodesis for chronic recurrent pleural effusions. Ann Intern Med. 1991; 115:778-82. [IDIS 288492] [PubMed 1929026]

6. Hamed H, Fentiman IS, Chaudary MA et al. Comparison of intracavitary bleomycin and talc for control of pleural effusions secondary to carcinoma of the breast. Br J Surg. 1989; 76:1266-7. [PubMed 2481558]

7. Ong KC, Indumathi V, Raghuram J et.al. A comparative study of pleurodesis using talc slurry and bleomycin in the management of malignant pleural effusions. Respirology. 2000; 5:99-103. [PubMed 10894097]

8. Zimmer PW, Hill M, Casey K et al. Prospective randomized trial of talc slurry vs bleomycin in pleurodesis for symptomatic malignant pleural effusions. Chest. 1997; 112:430-4. [IDIS 392697] [PubMed 9266880]

9. Noppen M, Degreve J, Mignolet M et al. A prospective, randomised study comparing the efficacy of talc slurry and bleomycin in the treatment of malignant pleural effusions. Acta Clin Belg. 1997; 52:258-62. [PubMed 9489119]

10. Fentiman IS, Rubens RD, Hayward JL. A comparison of intracavitary talc and tetracycline for the control of pleural effusions secondary to breast cancer. Eur J Cancer Clin Oncol. 1986; 22:1079-81. [PubMed 3536525]

11. Fentiman IS, Rubens RD, Hayward JL. Control of pleural effusions in patients with breast cancer. A randomized trial. Cancer. 1983; 52:737-9. [IDIS 173650] [PubMed 6190551]

12. Kuzdzal J, Sladek K, Wasowski D et al. Talc powder vs doxycycline in the control of malignant pleural effusion: a prospective, randomized trial. Med Sci Monit. 2003; 9:PI72-9. [PubMed 12824959]

13. Yim AP, Chan AT, Lee TW et al. Thoracoscopic talc insufflation versus talc slurry for symptomatic malignant pleural effusion. Ann Thorac Surg. 1996; 62:1655-8. [IDIS 377654] [PubMed 8957368]

14. Walker-Renard PB, Vaughan LM, Sahn SA. Chemical pleurodesis for malignant pleural effusions. Ann Intern Med. 1994; 120:56-64. [IDIS 323067] [PubMed 8250457]

15. Noppen M, Degreve J, Mignolet M et al. A prospective, randomised study comparing the efficacy of talc slurry and bleomycin in the treatment of malignant pleural effusions. Acta Clin Belg. 1997; 52:258-62. [PubMed 9489119]

16. Zimmer PW, Hill M, Casey K et al. Prospective randomized trial of talc slurry vs bleomycin in pleurodesis for symptomatic malignant pleural effusions. Chest. 1997; 112:430-4. [IDIS 392697] [PubMed 9266880]

17. Hamed H, Fentiman IS, Chaudary MA et al. Comparison of intracavitary bleomycin and talc for control of pleural effusions secondary to carcinoma of the breast. Br J Surg. 1989; 76:1266-7. [PubMed 2481558]

18. Ruckdeschel JC. Management of malignant pleural effusion: an overview. Semin Oncol. 1988; 15(Suppl 3):24-8. [PubMed 3293215]

19. Andrews CO, Gora ML. Pleural effusions: pathophysiology and management. Ann Pharmacother. 1994; 28:894-903. [IDIS 334463] [PubMed 7524816]

20. Hausheer FH, Yarbro JW. Diagnosis and treatment of malignant pleural effusion. Semin Oncol. 1985; 12:54-75. [PubMed 2579439]

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• Sterile Talc Prescribing Information (FDA)